When it comes to fresh seafood, Fort Myers doesn’t mess around. Whether you’re craving oysters by the water, buttery lobster rolls, or crispy, Southern-style fried shrimp, this Gulf Coast gem has something for every seafood lover. I spent some time combing through the top local favorites and hidden gems to bring you this ultimate list of the best seafood restaurants in Fort Myers as of July 2025.
1. Oxbow Bar & Grill
1300 Hendry St, Downtown Fort Myers
Dockside dining with a view? Yes, please. Oxbow is a stylish waterfront spot offering coastal cuisine, oysters, craft beer, and panoramic views of the Caloosahatchee River. The atmosphere is modern and casual, perfect for weekend brunch or sunset dinners.
2. Connors Steak & Seafood
10076 Gulf Center Dr, Fort Myers
Don’t let the word "steak" fool you—their seafood game is strong. Connors is known for wood-fired steaks and U.S.D.C.-inspected seafood. It's a polished yet comfortable setting with generous portions and consistent quality.
3. Deep Lagoon Seafood & Oyster House
14040 McGregor Blvd, Fort Myers
This one’s for the purists. Deep Lagoon sources directly from local fishermen and serves up Gulf Coast classics like grouper fingers, oysters Rockefeller, and tuna tataki. The vibe is clean and coastal, ideal for both casual bites and special occasions.
4. Prawnbroker Restaurant & Fish Market
13451-16 McGregor Blvd, Fort Myers
A Fort Myers institution since 1982, Prawnbroker combines a lively bar, top-tier seafood, and even a fish market. The menu features hand-selected seafood prepared fresh daily. Locals love it for both date night and fish-to-go.
5. Salty Papa’s Shrimp House
15271 McGregor Blvd, Suite 1, Fort Myers
Bayou meets beach at this local gem. Think Southern spices, real-fruit frozen drinks, and a pet-friendly courtyard. The menu is full of bold flavors, and the kitchen is serious about sourcing from the Gulf and Southern states.
6. Shrimp Shack
13361 Metro Pkwy, Fort Myers
No frills, all flavor. Started by two local women in 1998, this spot is known for ultra-fresh seafood, fast service, and a laid-back, friendly vibe. Great for families and anyone craving comfort food with Gulf flair.
7. Dixie Fish Company
714 Fishermans Wharf, Fort Myers Beach
This historic fish house (built in 1937) offers one of the best waterfront seafood experiences in town. Famous for whole fried fish and Yucatán shrimp, Dixie Fish is where Southern charm meets coastal cooking. Bonus: it was featured on Food Network.
8. Izzy’s Fish & Oyster
2282 First St, Downtown Fort Myers
New England seafood, Florida attitude. Izzy’s is a cool downtown joint with a modern vibe, offering build-your-own fish dishes, lobster rolls, and raw bar options. Great cocktails, too.
9. University Grill
7790 Cypress Lake Dr, Fort Myers
Established in 1997, University Grill mixes fresh seafood with steaks, martinis, and a classic supper club feel. It’s popular with the theater crowd, so grab a reservation before a show at Barbara B. Mann.
10. Cape Cod Fish Company
15501 Old McGregor Blvd, Fort Myers
Craving clam chowder or baked cod with a buttery crust? This New England-style seafood shack serves up authentic flavors in a laid-back setting. It’s a local favorite for a reason—hearty, satisfying, and fairly priced.
Final Thoughts:
Fort Myers is packed with seafood options, whether you're into white tablecloth service or eating a shrimp po'boy in flip-flops. These ten spots have earned their place for freshness, flavor, and that signature Southwest Florida hospitality. So next time you're hungry for something from the sea, consider this your go-to seafood crawl checklist.